Detalhe da pesquisa
1.
Identification and structural validation of purine nucleoside phosphorylase from Plasmodium falciparum as a target of MMV000848.
J Biol Chem
; 300(1): 105586, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38141766
2.
Short tandem repeat polymorphism in the promoter region of cyclophilin 19B drives its transcriptional upregulation and contributes to drug resistance in the malaria parasite Plasmodium falciparum.
PLoS Pathog
; 19(1): e1011118, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36696458
3.
Genomic, transcriptomic, and metabolomic analysis of Oldenlandia corymbosa reveals the biosynthesis and mode of action of anti-cancer metabolites.
J Integr Plant Biol
; 65(6): 1442-1466, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-36807520
4.
Whole-Cell Phenotypic Screening of Medicines for Malaria Venture Pathogen Box Identifies Specific Inhibitors of Plasmodium falciparum Late-Stage Development and Egress.
Antimicrob Agents Chemother
; 64(5)2020 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32071059
5.
Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites.
PLoS Pathog
; 14(3): e1006930, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29538461
6.
A comprehensive RNA handling and transcriptomics guide for high-throughput processing of Plasmodium blood-stage samples.
Malar J
; 19(1): 363, 2020 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33036628
7.
Gene copy number variation in natural populations of Plasmodium falciparum in Eastern Africa.
BMC Genomics
; 19(1): 372, 2018 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29783949
8.
Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance.
PLoS Biol
; 13(4): e1002132, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25901609
9.
Declining Efficacy of Artemisinin Combination Therapy Against P. Falciparum Malaria on the Thai-Myanmar Border (2003-2013): The Role of Parasite Genetic Factors.
Clin Infect Dis
; 63(6): 784-791, 2016 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27313266
10.
Structural polymorphism in the promoter of pfmrp2 confers Plasmodium falciparum tolerance to quinoline drugs.
Mol Microbiol
; 91(5): 918-34, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24372851
11.
Transcriptional variation in the malaria parasite Plasmodium falciparum.
Genome Res
; 22(5): 925-38, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22415456
12.
Dynamic epigenetic regulation of gene expression during the life cycle of malaria parasite Plasmodium falciparum.
PLoS Pathog
; 9(2): e1003170, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23468622
13.
A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells.
Proc Natl Acad Sci U S A
; 109(26): E1772-81, 2012 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22619330
14.
Genome-wide analysis in Plasmodium falciparum reveals early and late phases of RNA polymerase II occupancy during the infectious cycle.
BMC Genomics
; 15: 959, 2014 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25373614
15.
H2A.Z and H2B.Z double-variant nucleosomes define intergenic regions and dynamically occupy var gene promoters in the malaria parasite Plasmodium falciparum.
Mol Microbiol
; 87(6): 1167-82, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23373537
16.
Quantitative proteomics reveals new insights into erythrocyte invasion by Plasmodium falciparum.
Mol Cell Proteomics
; 11(2): M111.010645, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22023809
17.
Sterile protection against P. vivax malaria by repeated blood stage infection in the Aotus monkey model.
Life Sci Alliance
; 7(3)2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38158220
18.
Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug development.
Cell Chem Biol
; 31(4): 743-759.e8, 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38593807
19.
Analysis of subtelomeric virulence gene families in Plasmodium falciparum by comparative transcriptional profiling.
Mol Microbiol
; 84(2): 243-59, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22435676
20.
Quantitative time-course profiling of parasite and host cell proteins in the human malaria parasite Plasmodium falciparum.
Mol Cell Proteomics
; 10(8): M110.006411, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21558492